Original church: 311-314 by Pope Melchiades or late 400s

Rebuilt church: 847-855 by Pope Leo IV

Rebuilt smaller church: 1111 by Pope Paschal II

Given to Augustinian nuns: 1560 by Pope Pius IV

Apse renovations: 1621-1623 by Giovanni da San Giovanni for Cardinal Giovanni Mellini

Restoration: 1912-1914 by Antonio Munoz

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• It is unclear if the church was constructed in the 4th or 5th century but what is clear is that it was soon well known as SS. Quattro Coronati (Four Crowned Saints)

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• Pope Leo IV (847-855) built a new church and, from the cemetery on the Via Labicana, brought the relics of the Quattro Coronati and, soon after, the relics of the five sculptors for Pannonia. The relics of the Quattro Coronati, traditionally named as Severus, Victorinus, Carpophorus, and Severinus, are found in the crypt. They were martyred by Diocletian (284-305) for not worshiping a statue of the pagan god Asclepius. The relics of the five sculptors of Pannonia, traditionally named Claudius, Nicostratus, Castor, Sempronianus, and Simplicius, are also found in the crypt. They were martyred for not making a sculpture of the pagan god Asclepius

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• After damage in the sack of Rome by the Normans (1084), Pope Paschal II (1099-1118) reconstructed it as a smaller church in 1111. The renovation in 1912-1914 restored much of the church to what it was under Pope Pascal II